The Foo lab uses a variety of ‘omic approaches to uncover key disease-causing target genes, especially for heart failure. We explore a variety of Cardiovascular related research including Cardiac Epigenetics and Epigenomics.
Heart Failure is characterized by a hallmark change in gene expression programmes. Epigenetics or chromatin modulations may, therefore, be the means by which myriad initiating causes are integrated to produce the final common pathway of heart failure.
Heart failure is the final common pathway for cardiovascular disease, regardless of their initiating causes.
Mortality of heart failure is ~50% in 5 years, rivaling that of even some cancers. Heart failure incidence is increasing with an ever ageing world population. New treatment options for heart failure are urgently needed.
This underpins a serious and urgent need for new ways of treating cardiovascular disease and heart failure.
Useful links to learn more about Heart Failure: